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The Prevalence of Hepatitis B and C Virus in Patients With End-Stage Kidney Disease on Regular Hemodialysis in Duhok, Iraq: A Brief Report

عنوان مقاله: The Prevalence of Hepatitis B and C Virus in Patients With End-Stage Kidney Disease on Regular Hemodialysis in Duhok, Iraq: A Brief Report
شناسه ملی مقاله: JR_JCMI-7-1_006
منتشر شده در در سال 1399
مشخصات نویسندگان مقاله:

Zana Sidiq Mohammed Saleem
Ibrahim A Naqid
Nawfal R Hussein
Sidra Jalal Mohammad
Jajeen Shaaban Noaman
Rajeen Salih Haji
Vin Ahmed Haji
Zainnab Muhsin Hussein
Piran Hussamaldin Mohammed

خلاصه مقاله:
Background and aim: Hepatitis B and C virus (HBV and HCV) infections are considered as major global public health concerns. Chronic infections may lead to liver cirrhosis, hepatic failure, and hepatocellular carcinoma. Therefore, the aim of this study was to investigate the prevalence of HBV and HCV infections in patients with end-stage kidney disease (ESKD) and on regular hemodialysis in Duhok located in the Kurdistan region of Iraq. Methods: A cross-sectional study was conducted in Duhok, Iraq between January ۲۰۱۹ and October ۲۰۱۹. During this period, a total of ۱۴۳ patients within the age range of ۹-۷۲ years old with ESKD visited the Duhok dialysis center for regular hemodialysis. Enzyme-linked immunosorbent assay (ELISA) was conducted to test HBV and HCV positivity and then HBV viral load was tested by the real-time polymerase chain reaction (RTPCR). Finally, HCV positivity was confirmed by the Xpert HCV quantification assay. Results: Among the recruited samples, ۵ out of ۱۴۳ (۳.۴۹%) patients were positive for HBV while HBV viral load for those patients was undetected. On the other hand, ۳/۱۴۳ (۲.۱%) patients tested positive for HCV Ab. All these ۳ patients were also confirmed positive by the RT-PCR. Conclusions: ESKD patients on regular analysis showed a low prevalence of HBV and HCV in the Duhok dialysis center. An effective infection control program, vaccination, and treatment of HCV make the elimination of HBV and HCV feasible in such a group.

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1911897/