Ali Maleki - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Mohammad Hassan Pouriayevali - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Mahsa Tavakoli - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Zahra Ahmadi - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Farideh Niknam Oskouei - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Zahra Nejatipour - Genetics and Molecular Medicine Department, Medical Faculty, Zanjan University of Medical Science, Zanjan, Iran
Tahmineh Jalali - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran
Mostafa Salehi-Vaziri - COVID-۱۹ National Reference Laboratory, Pasteur Institute of Iran, Tehran, Iran; Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran

In the SARS-CoV-۲ pandemic, the seasonal viral respiratory infections had a minimum prevalence due to public health precautions to reduce the risk of getting Coronavirus Disease ۱۹ (COVID-۱۹). There have been reports of COVID-۱۹ coinfection with influenza, respiratory syncytial virus (RSV), and seasonal coronaviruses during the pandemic. Here, we report a case in which the patient had sequential respiratory infections of human coronavirus HKU۱ (HCoV-HKU۱) and SARS-CoV-۲ in a fully vaccinated, healthy person. It should be noted that other seasonal coronaviruses that could cause symptomatic RTIs might be misdiagnosed clinically with COVID-۱۹. Hence, we highly recommend monitoring and follow-up of symptomatic patients with negative SARS-COV-۲ RT-PCR results.

SARS-CoV-۲, COVID-۱۹, HCoV-HKU۱, Coronaviruses, Sequential infection