CIVILICA We Respect the Science
(ناشر تخصصی کنفرانسهای کشور / شماره مجوز انتشارات از وزارت فرهنگ و ارشاد اسلامی: ۸۹۷۱)

Tocilizumab in Post Hematopoietic Stem Cell Transplant COVID-۱۹: A Pediatric Case Report

عنوان مقاله: Tocilizumab in Post Hematopoietic Stem Cell Transplant COVID-۱۹: A Pediatric Case Report
شناسه ملی مقاله: JR_JMMI-9-4_008
منتشر شده در در سال 1400
مشخصات نویسندگان مقاله:

Tahereh Rostami - Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Neda Alijani - Department of Infectious Diseases, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Azadeh Kiumarsi - Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Soroush Rad - Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Seied Amirhosein Mirhoseini - Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Mohammadreza Rostami - Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Amir Hesabi - Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Seyed Ali Mousavi - Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
Seied Asadollah Mousavi - Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran

خلاصه مقاله:
Hematopoietic stem cell transplantation (HSCT) severely undermines the recipients' immune status and makes them prone to complications following viral infection. Here, we report a ۳-year-old boy with mucopolysaccharidosis type VI who acquired SARS-CoV-۲ infection after HSCT. The boy was diagnosed with SARS-CoV-۲ during the post-transplant period (۱۹ days after HSCT) when dealing with acute graft versus host disease (GVHD). He was successfully treated with remdesivir and tocilizumab and recovered. Well-timed treatment with tocilizumab might reduce the risk of invasive mechanical ventilation and death in patients with severe COVID-۱۹ pneumonia in the early post HSCT period.

کلمات کلیدی:
Post Hematopoietic Stem Cell Transplantation, COVID-۱۹, Mucopolysaccharidosis

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1917586/