Hamzeh Hosseinzadeh - Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Parichehr Mazuji - Anesthesiologist, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Samad Eslam Jamal Golzari - Associate Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Introduction: Ephedrine and phenylephrine are the preferred vasopressors for preventing SAIH in the elderly. Our study's goal was to assess how well prophylactic intravenous (IV) ephedrine or N/S infusions prevented hypotension and decreased CO after SA in patients older than ۶۰ undergoing elective orthopedic surgery. Material and Methods: The patients were randomly assigned to one of the three groups using sealed envelope randomization for the administration of the prescribed medication. Thirty milliliters of ۰.۹% NaCl were infused into the C group (control group) ۳۰ minutes after SA. Thirty minutes after SA, the E group (ephedrine group) received a continuous infusion of ۳۰ ml of ۰.۹% NaCl and ۲۰ mg of ephedrine. Following SA, a volumetric IV pump was used to begin the infusion of the prescribed treatment medication in all groups. Using the AESCULON, OSYPCA MEDICAL, ۲۰۱۱, monitor, we measured non-invasive blood pressure, non-invasive CO using the thoracic electrical bioimpedance (TEB) method, heart rate, and pulse oximetry (SpO۲). Results: A brief statistically significant decrease in MAP was observed in the P group ۱۰ and ۲۰ minutes after the block, but by the time the measurements were complete, MAP had nearly reached baseline levels. In the E group, MAP was preserved following SA. At the conclusion of the measurements, there were no differences between the P and E group, but the decrease in MAP was noticeably greater in the C group than the E and P group. In the C and P groups, CI after SA decreased non-significantly, while in the E group, CI significantly increased after SA. Conclusion: In conclusion, our research demonstrates that we can maintain MAP following SA by combining the Ringers solution infusion with an infusion of ephedrine or phenylephrine.

hemodynamic status, Elderly, Spinal anesthesia, Ephedrine Infusion