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Synthesis, feasibility study of production of singlet oxygen and hydroxyl radical and performance in antibacterial activity of ZnS:Eu QDs

عنوان مقاله: Synthesis, feasibility study of production of singlet oxygen and hydroxyl radical and performance in antibacterial activity of ZnS:Eu QDs
شناسه ملی مقاله: JR_JRCC-4-11_002
منتشر شده در در سال 1401
مشخصات نویسندگان مقاله:

Merat Karimi - Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
Ehsan Sadeghi - Department of Physics, University of Kashan, Kashan, Iran
Samira Khosravi Bigdeli - Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
Mostafa Zahedifar - Department of Physics, University of Kashan, Kashan, Iran

خلاصه مقاله:
ZnS:Eu nanoparticles also have the ability to produce reactive oxygen species that can be used to treat cancers. Eu doped zinc sulfide quantum dots (QDs) were prepared by the chemical Co-precipitation method. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and infrared Fourier transform (FT-IR) analysis were used to characterize the quantum dots. The photoluminescence spectrum (PL) of ZnS:Eu QD in excitation wavelength of ۲۸۰ nm shows two emission peaks at ۳۸۴ and ۷۱۵ nm. In order to use these QDs as photosensitizer in photodynamic therapy, anthracene and methylene blue chemical detectors were used for detection of singlet oxygen and hydroxyl radical, respectively. The significant point for these quantum dots is that, in addition to production of hydroxyl radical, they also have the ability to produce singlet oxygen with UV-C radiation. The antimicrobial effect of ZnS:Eu QDs was also investigated using a disc diffusion method on ۱۱ microbial strains. Zinc sulfide nanoparticles with Europium impurities can have good medical application due to their good antibacterial activity and ability to produce reactive oxygen species.ZnS:Eu nanoparticles also have the ability to produce reactive oxygen species that can be used to treat cancers. Eu doped zinc sulfide quantum dots (QDs) were prepared by the chemical Co-precipitation method. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and infrared Fourier transform (FT-IR) analysis were used to characterize the quantum dots. The photoluminescence spectrum (PL) of ZnS:Eu QD in excitation wavelength of ۲۸۰ nm shows two emission peaks at ۳۸۴ and ۷۱۵ nm. In order to use these QDs as photosensitizer in photodynamic therapy, anthracene and methylene blue chemical detectors were used for detection of singlet oxygen and hydroxyl radical, respectively. The significant point for these quantum dots is that, in addition to production of hydroxyl radical, they also have the ability to produce singlet oxygen with UV-C radiation. The antimicrobial effect of ZnS:Eu QDs was also investigated using a disc diffusion method on ۱۱ microbial strains. Zinc sulfide nanoparticles with Europium impurities can have good medical application due to their good antibacterial activity and ability to produce reactive oxygen species.

کلمات کلیدی:
Nanoparticles, ZnS:Eu, Co-precipitation, Antibacterial, Cancer

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1921716/