H.R POUR eSLAMI - Associate Professor of Pediatric Dentistry, School of Dentistry & Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran
GH.R Moshtaghi - Associate Professor of Biochemistry, Afzalipour School of Medicine & Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
A Hori - Assistant Professor of Pediatric Dentistry, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
M SHarifi - Assistant Professor of Pediatric Dentistry, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
H Ziaaddini - Resident of Orthodontics, School of Dentistry, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

Background & Aims: Sever early childhood caries (SECC) is a multifactor common disease that unfortunately there have been a lot of unknown points about it. This study was performed to compare the levels of total S-IgA in children with and without SECC. Methods: In this cross-sectional study ۴۴ children aged ۶-۲۴ months were divided into two groups of with SECC (n=۲۰) and without SECC (n=۲۴). The two groups were compared for the concentration of S-IgA assessed with Nephlometric method. The obtained data were analyzed by using t-test and through SPSS ۱۵ software. Results: Mean saliva concentration of S-IgA in children with SECC (۱۸.۳۰ mg/dl) was higher than that in children without SECC (۹.۴۶ mg/dl) and this difference was statistically Significant (P<۰.۰۵). Conclusion: According to this study, the hypothesis of lower levels of S-IgA in children with SECC might be rejected.

immunoglobulins, Saliva, Dental Caries