Naeme Javid - Golestan university of medical sciences
Teena Dadgar - Shiraz Azad university
Behnaz Khodabakhshi - Infectious disease research center, Golestan university of medical sciences,
Masoud Bazour - Golestan university of medical sciences
Mehdi Sedaghat - Health deputy, Golestan university of medical sciences
Sepideh Bakhshandeh-nosrat - Infectious disease research center, Golestan university of medical sciences,
Somayeh Rahimi - Golestan university of medical sciences
Ezzat allah Ghaemi - Infectious disease research center, Golestan university of medical sciences

Southern margin of the Caspian Sea due to keeping of domestic animals and abundance of surface water reservoirs is prone to infection with Leptospira sp.. This study was performed to determine anti-Leptospira antibody frequency in Golestan province, southeast of the Caspian Sea in the north of Iran. This study was performed on ۱۰۲۸ people in Golestan province. Sampling was stratified. Leptospira antibody (IgG) was measured with DRG (USA) enzyme linked immunosorbent assay (ELISA). ۱۰۷ cases (۱۰.۴%) had anti-Leptospira sera antibody. Distribution of positive cases was ۵۹ (۱۰.۹%) in women and ۴۸ (۹.۸%) in men. Most positive cases were in the ۳۵-۴۴ years old group. The frequency of positive cases in the people who was living in the towns and villages in Golestan Province were ۹.۴% and ۱۱.۱%, respectively. No significant difference was seen between the groups.According to the data presented in this study and compared to the published data it was shown that the frequency of antibody against Leptospira in Golestan province is lower than both Guilan and Mazandaran provinces in the north of Iran.

Leptospira, Seroepidemiology, Antibody, Iran