R Vakili - Associate Professor of Pediatrics
A Ghasemi - Pediatrician, Mashhad University of Medical Sciences and Health Services, Mashhad, Iran

Rud syndrome consists of mental retardation, epilepsy, ictihyosis, dentition and skeleton defect. We report a case of Rud syndrome that have clinical, radiological and biochemical characteristics of rickets. Alteration in epidermal cholestrol metabolism, limited sun exposure or associated defects may explain this condition. All such patients need life – long rickets prophylaxis with vitamin D supplements (۴۰۰ IU/day , A diatary intak alone can not be relied upon.

Ichthyosis, Rud syndrome, rickets