Mehmet Nuri ACIK - Bingol University, Veterinary Faculty, Microbiology Department, ۱۲۰۰۰ Bingol/TURKEY
Gülden Karlıdağ - ۲University of Health Sciences, Fethi Sekin City Hospital, Clinic of Infectious Diseases and Clinical Microbiology, Elazig, Turkey
Burcu Karagülle - Department of Microbiology, Faculty of Veterinary Medicine, University of Firat, Elazig, Turkey
Tugce Atcali - Department of Physiology, Faculty of Veterinary Medicine, University of Bingol, ۱۲۰۰۰, Bingol-Turkey;
Cihat Uçar - Department of Physiology, Faculty of Medicine, University of Adıyaman, Adıyaman, Turkey
Faruk Dişli - Department of Physiology, Faculty of Medicine, University of Inonu, Malatya, Turkey
Seda Yakut - Department of Histology and Embryology, Faculty of Veterinary Medicine, University of Bingol, ۱۲۰۰۰, Bingol-Turkey
Sedat Yıldız - Department of Physiology, Faculty of Medicine, University of Inonu, Malatya, Turkey
Burhan CETINKAYA - Firat University

This study was conducted to investigate variations in SarsCoV-۲-specific IgG levels over a ۵-month period in healthcare workers who received two doses of CoronaVac vaccine.  Blood samples were collected from ۱۲۲ participants on days ۱۴, ۵۶ and ۱۵۰ following the second dose of the vaccination. SarsCoV-۲ specific IgG antibody titres of the participants were measured using the QuantiCOR ELISA kit. Demographic data of the participants were recorded. Seropositivity on ۱۴th, ۵۶th and ۱۵۰th days in the previously uninfected group was ۴۴.۸%, ۵۰.۷% and ۳۲.۸%, respectively. In the previously infected group, seropositivity was detected in ۸۷.۲%, ۹۲.۷% and ۴۳.۶% of the participants, respectively. While a statistically significant difference was determined between the two groups in terms of seropositivity on the ۱۴th and ۵۶th days, no statistical difference was found on the ۱۵۰th day. The data of this study indicated that the CoronaVac vaccine provided sufficient immunity in previously infected individuals, though the duration of immunity was short. It is suggested that CoronaVac vaccine would be more appropriate to use as a booster in order to increase the effectiveness of a vaccine rather than the first vaccination, or to vaccinate people who have been infected before.

COVID-۱۹, Healthcare workers, CoronaVac, IgG, Elisa