Evaluation of the Probable linkage between Cytomegalovirus and Type ۲ diabetes
عنوان مقاله: Evaluation of the Probable linkage between Cytomegalovirus and Type ۲ diabetes
شناسه ملی مقاله: JR_IJMCM-11-1_005
منتشر شده در در سال 1400
شناسه ملی مقاله: JR_IJMCM-11-1_005
منتشر شده در در سال 1400
مشخصات نویسندگان مقاله:
negin Azadan - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Atosa Ferdousi - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Mohammad Hassan Shahhosseini - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
خلاصه مقاله:
negin Azadan - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Atosa Ferdousi - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Mohammad Hassan Shahhosseini - Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Some recent investigations, have suggested a probable linkage between cytomegalovirus (CMV) and developing diabetes. But still there is not enough literature to assess the rate of this association. To this purpose, in the present study for detecting CMV genome, serum samples of ۵۰ type ۲ diabetic patients as the test group with an optimized PCR reaction were tested. Sex, age and A۱C parameter related to this group were recorded too. The specificity of the PCR test was ۱۰۰% and its sensitivity was ۱۰۰ copy of the viral genome in the sample. The related results were compared with the control group that was included ۵۰ non-diabetic participants. The CMV genome did not find in None of these ۱۰۰ samples. No related effects were observed between sex or amount of A۱C and association of CMV genome in these patients. However, it seems that the age parameter is effective in this regard. Comparing these participants with some other similar research suggest that this association rate is not very high and the virus only in elderly age can be considered as a probable risk factor. Thus, for managing diabetes should be more concentrated on the well-known factors such as obesity or unhealthy lifestyle.
کلمات کلیدی: Cytomegalovirus, Diabetes, Polymerase chain reaction (PCR), Herpesviridae, elderly age , lifestyle
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1932732/