Saeid Mahdavi Omran - Infectious Diseases and Tropical Medicine Research Center, Health Research Center, Babol University of Medical Sciences, Babol, Iran; Department of Medical Parasitology and Mycology, School of Medicine, Babol University of Medical

This clinical trial study was performed on ۱۴۴ patients suspect to have otitis externa between ۲۰۱۷ and ۲۰۱۸ in the ENT clinic of Ayatollah Rouhani hospital in Babol. For the treatment on the same day, the patients were categorized into two groups randomly. In the first group, after suction clearance, ciprofloxacin powder and betamethasone ointment were used, while in the second group after suction clearance, ciprofloxacin drop and betamethasone drop were used in the ear canal. All patients reevaluated after one week. After preparation of the results of culture of the samples, ۸۳ individuals including ۴۴ in the first group (ciprofloxacin powder and betamethasone ointment) and ۳۹ subjects in the second group (ciprofloxacin drop and betamethasone drop) had bacterial otitis externa. The mean intensity of pain in the first and second groups was ۲.۶۱±۲.۱۳ and ۲.۸.۰۰, respectively which showed a significant difference (Pvalue<۰.۰۰۱). The itching was ۳۸ (۸۶.۴%) and ۶ (۱۵.۴%) cases in the first and second groups, respectively, which showed a significant difference (Pvalue<۰.۰۰۱). The discharge in the first and second groups was ۱۰ (۲۲.۷%) and ۱ (۲.۶%) respectively which again had a significant difference (Pvalue=۰.۰۰۷). The extent of diminished hearing in the first and second groups was ۱۷ (۳۸.۶%) and ۰ (۰%), respectively, indicating a significant difference (Pvalue<۰.۰۰۱). Finally, inflammation in the first and second groups was ۲۰ (۴۵.۵%) and ۰ (۰%), showing a significant difference (Pvalue<۰.۰۰۱). This study indicated use of ciprofloxacin powder and betamethasone ointment is less effective than applying ciprofloxacin drop and betamethasone drop.

antibiotic, bacterial infection, direct examination, mycology, culture