Khorshid Ebrahimi - Department of Microbiology, Babol Branch, Islamic Azad University, Babol, Iran
Majid Alipour - Department of Microbiology, Babol Branch, Islamic Azad University, Babol, Iran
Yousef Yahyapour - Department of Microbiology, Infectious Diseases and Tropical Medicine Research Center, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran

Staphylococcus saprophyticus is an important agent of urinary tract infections (UTIs), especially among young women. The aim of this study was to identify S. saprophyticus as a common cause of urinary tract infections and determine their antibiotic susceptibility. In this study, ۵۱۲۳۵ clinical samples were collected from therapeutic centers of Mazandaran. S. saprophyticus was confirmed by the real- time PCR technique through rrs gene and their antibiotic resistance pattern determined by disc diffusion method. Of the ۵۱۲۳۵ cultivated samples, only ۲۱۰۱ (۴.۱%) cases had significant bacteriuria. In this study, the prevalence of S. saprophyticus was ۲.۴۷%. Escherichia coli was the most common bacterium isolated from patients with UTIs at the rate of ۶۱.۰۶%. S. saprophyticus showed the highest frequency of antibiotic resistance to erythromycin at the rate of ۸۰% and ampicillin and cefotaxime were ranked with the frequency of ۵۵ and ۱۷.۵%, respectively. The present study shows that bacterial resistance is a potential problem in Mazandaran province.

Urinary Tract Infection, Staphylococcus saprophyticus, Antibiotic Resistance, rrs Gene, PCR