Intraosseous Regional Administration of Vancomycin Prophylaxis for Primary and Revision Total Knee Arthroplasty
عنوان مقاله: Intraosseous Regional Administration of Vancomycin Prophylaxis for Primary and Revision Total Knee Arthroplasty
شناسه ملی مقاله: JR_TABO-12-3_010
منتشر شده در در سال 1403
شناسه ملی مقاله: JR_TABO-12-3_010
منتشر شده در در سال 1403
مشخصات نویسندگان مقاله:
E. Carlos RODRIGUEZ-MERCHAN - Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain
Carlos A. Encinas-Ullan - Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain
خلاصه مقاله:
E. Carlos RODRIGUEZ-MERCHAN - Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain
Carlos A. Encinas-Ullan - Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain
The advantages of prophylaxis with intraosseous regional administration (IORA) of vancomycin for periprosthetic joint infection (PJI) in primary and revision total knee arthroplasty (TKA) include the ability to deliver antibiotics directly to the surgical bed and avert systemic delivery; the ability to precisely time and quickly administer vancomycin to achieve the highest concentrations at the beginning and throughout the surgical procedure; and the ability to avert several common and potentially serious adverse effects of intravenous vancomycin. Indications for IORA of vancomycin prophylaxis include the following clinical scenarios: revision TKA; obesity; diabetes; beta-lactam allergy; known colonization with methicillin-resistant Staphylococcus aureus (MRSA); individuals coming from institutions with a high MRSA incidence; previous ligamentous surgical procedure or osteotomy; current or recent smokers; in the primary TKA setting if the individual is considered high-risk as defined by the criteria above; and during reimplantation following ۲-stage exchange for PJI. The advantages of prophylaxis with intraosseous regional administration (IORA) of vancomycin for periprosthetic joint infection (PJI) in primary and revision total knee arthroplasty (TKA) include the ability to deliver antibiotics directly to the surgical bed and avert systemic delivery; the ability to precisely time and quickly administer vancomycin to achieve the highest concentrations at the beginning and throughout the surgical procedure; and the ability to avert several common and potentially serious adverse effects of intravenous vancomycin. Indications for IORA of vancomycin prophylaxis include the following clinical scenarios: revision TKA; obesity; diabetes; beta -lactam allergy; known colonization with methicillin-resistant Staphylococcus aureus (MRSA); individuals coming from institutions with a high MRSA incidence; previous ligamentous surgical procedure or osteotomy; current or recent smokers; in the primary TKA setting if the individual is considered high -risk as defined by the criteria above; and during reimplantation following ۲-stage exchange for PJI. Level of evidence: IIILevel of evidence: III
کلمات کلیدی: Intraosseous regional administration, Periprosthetic joint infection, Primary, Revision, Total knee arthroplasty, Vancomycin prophylaxis
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1933408/