Devi - Department of CSE Annamacharya Institute of Technology and Sciences, Tirupati, India.
Ashok - Department of Information Science and Engineering, BMS Institute of Technology and Management, Bengaluru, Karnataka.
Gowda - Department of Machine Learning (AI-ML) BMS College of Engineering, Bangalore, India.
Sumalatha - Department of Database Systems, School of Computer Science and Engineering, Vellore Institute of Technology, Vellore - ۶۳۲۰۱۴, Tamilnadu, India.
Kadiravan - Department of Computer Science and Engineering, Koneru Lakshmaiah Education Foundation, Vaddeswaram, AP, India.
Painam - Department of Electronics and Communication Engineering, Kallam Haranadhareddy Institute of Technology (Autonomous), NH-۱۶, Chowdavaram, Guntur, Andhra Pradesh, India.

Cancer is an abnormal cell growth that occurs uncontrollably within the human body and has the potential to spread to other organs. One of the primary causes of mortality and morbidity for people is cancer, particularly lung cancer. Lung cancer is one of the non-communicable diseases (NCDs), causing ۷۱% of all deaths globally, and is the second most common cancer diagnosed worldwide. The effectiveness of treatment and the survival rate of cancer patients can be significantly increased by early and exact cancer detection. An important factor in specifying the type of cancer is the histopathological diagnosis. In this study, we present a Simple Convolutional Neural Network (CNN) and EfficientNetB۳ architecture that is both straightforward and efficient for accurately classifying lung cancer from medical images. EfficientnetB۳ emerged as the best-performing classifier, acquiring a trustworthy level of precision, recall, and F۱ score, with a remarkable accuracy of ۱۰۰%, and superior performance demonstrates EfficientnetB۳’s better capacity for an accurate lung cancer detection system. Nonetheless, the accuracy ratings of ۸۵% obtained by Simple CNN also demonstrated useful categorization. CNN models had significantly lower accuracy scores than the EfficientnetB۳ model, but these determinations indicate how acceptable the classifiers are for lung cancer detection. The novelty of our research is that less work is done on histopathological images. However, the accuracy of the previous work is not very high. In this research, our model outperformed the previous result. The results are advantageous for developing systems that effectively detect lung cancer and provide crucial information about the classifier’s efficiency.

Lung cancer, Convolutional Neural Network (CNN), Histopathological Images, Transfer Learning, Lung Cancer Detection