Epidemiology and Survival of the Patients with Tuberculosis Covered by the Zabol Tuberculosis Center from ۲۰۰۶ to ۲۰۱۴

Background: Tuberculosis (TB) primarily targets the lungs and stands as the leading cause of death globally among diseases caused by a single agent. It is estimated that one-third of the world›s population is infected with TB. This study was undertaken due to the significant presence and incidence of TB in Zabol, an endemic city in Iran.Methods: We examined patient records (n=۴۰۹۲) spanning from ۲۰۰۶ to ۲۰۱۴, analyzing the data using SPSS. The Kaplan-Meier model was employed to assess patient survival rates, the Cox regression model helped identify factors affecting survival and mortality, and the classic Mantel-Haenszel method was utilized to calculate the mortality rate.Results: The patients’ mean age was ۵۳.۹۷ years, with a standard deviation of ۲۰.۵۵. Females comprised ۵۹.۷۸% of the study population, and ۸۴.۹۳% of the TB cases were pulmonary. Furthermore, ۸۹.۸۵% of the patients underwent successful treatment. Throughout the study period, there were ۲۴۰ recorded deaths among TB patients. The average survival duration for patients was ۲۶۳۸ days, with a five-year survival rate of ۷۵%. An increase in age every ۱۰ years significantly raised the risk of death among TB patients (P<۰.۰۵). However, no significant impact on patient survival was observed in relation to other variables, such as gender, history of recurrence, treatment delay, place of conflict, residency, and nationality.Conclusion: The findings of this study can provide useful information so that planners and health officials can take effective measures with appropriate interventions in order to diagnose the disease faster and follow up with appropriate treatment.

Keywords:

Epidemiology , Tuberculosis , Survival analysis