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Antifungal Potential of Honey against Dermatophytes: A Comprehensive Study on Isolates from Children and Farmers in Wukari, North East Nigeria

عنوان مقاله: Antifungal Potential of Honey against Dermatophytes: A Comprehensive Study on Isolates from Children and Farmers in Wukari, North East Nigeria
شناسه ملی مقاله: JR_IJABBR-12-2_008
منتشر شده در در سال 1403
مشخصات نویسندگان مقاله:

Anyiam Vivan Ifeoma - Department of Microbiology, Faculty of Science, Federal University Otuoke, Bayelsa State, Nigeria
Imarenezor Edobor Peter Kenneth - Department of Microbiology, Faculty of Science, Federal University Otuoke, Bayelsa State, Nigeria
Abhadionmhen Onolunosen Abel - Department of Microbiology, Federal University Wukari Taraba State, Nigeria
Ofiri Pascal Ngozi - Technical Officer-PMTCT, PEAD/Adolescent ECEWS Osun State AP۳ Lead, Nigeria

خلاصه مقاله:
This study explores the antifungal properties of honey against dermatophytes isolated from children and farmers in Wukari, Nigeria, addressing the global public health concern of dermatophytosis. Dermatophytes such as Trichophyton species, Epidermophyton floccosum, and Microsporum canis were identified in skin, hair, and nail samples. Through agar well diffusion and minimum inhibitory concentration (MIC) methods, the study demonstrated concentration-dependent inhibitory effects of honey on these dermatophytes, with substantial zones of inhibition. Notably, Trichophyton species exhibiting a maximum zone diameter of ۳۶ mm at ۱۰۰% honey concentration followed by Epidermophyton floccosum (۲۵ mm) and Microsporum canis (۴۰ mm). MIC results at a ۶۰% honey dilution showed very scanty growth for Trichophyton species and Epidermophyton floccosum, while Microsporium canis displayed no growth after both five and seven days of culture. The findings suggest honey's potential as an alternative antifungal agent against dermatophytes amid increasing antimicrobial resistance. Future research should focus on identifying honey's specific bioactive components and conducting clinical trials for practical application.

کلمات کلیدی:
dermatophytosis, Honey, Antifungal activity, antimicrobial resistance

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1954332/