Furan: A Promising Scaffold for Biological Activity
عنوان مقاله: Furan: A Promising Scaffold for Biological Activity
شناسه ملی مقاله: JR_IJABBR-12-2_005
منتشر شده در در سال 1403
شناسه ملی مقاله: JR_IJABBR-12-2_005
منتشر شده در در سال 1403
مشخصات نویسندگان مقاله:
Gangurde Punam Nivrutti - Divine College of Pharmacy Satana Dist. Nashik, Maharastra, India
خلاصه مقاله:
Gangurde Punam Nivrutti - Divine College of Pharmacy Satana Dist. Nashik, Maharastra, India
It was shown that several bioactive aromatic compounds with biological applications have the furan nucleus watch Numerous significant synthetic compounds include furan scaffold, which offers a helpful therapeutic idea and is found to have strong affinity for a range of receptors, assisting in the synthesis of novel, advantageous derivatives The antibacterial, antifungal, antiviral, anti-inflammatory, analgesic, antidepressant, antianxiolytic, anti-Parkinson, anti-glaucoma, muscle-relaxant, antihypertensive, diuretics, anti-ulcer, anti-aging, and anti-cancer effects of furan derivatives make them frequently utilized. Diverse furan derivatives have piqued the interest of researchers. Furan is a colourless liquid that boils almost at ambient temperature and is highly volatile and combustible. Electron-Rich Nature: Furan rings have the ability to engage in a variety of electrical interactions with biomolecules due to their electron-rich nature. This characteristic might make it easier to attach strongly to biological targets like enzymes or receptors, which would affect how they function. Aromaticity: Furan's aromatic properties may give the compounds stability, which could improve their metabolic stability and bioavailability. Numerous natural compounds and pharmaceutical molecules are known to depend heavily on aromatic systems for their bioactivity.Functional Group Diversity: A wide variety of derivatives can be synthesized by simply modifying furan scaffolds with different functional groups.
کلمات کلیدی: Furan, heterocyclic compound, Biological activity
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1954335/