The Effects of Aloe Vera Cream on the Alar Scar in Rhinoplasty, A Randomized Double-Blind Controlled Trial
عنوان مقاله: The Effects of Aloe Vera Cream on the Alar Scar in Rhinoplasty, A Randomized Double-Blind Controlled Trial
شناسه ملی مقاله: JR_IJOTO-36-3_008
منتشر شده در در سال 1403
شناسه ملی مقاله: JR_IJOTO-36-3_008
منتشر شده در در سال 1403
مشخصات نویسندگان مقاله:
Reza Kaboodkhani - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohsen Sarikhani - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Tayebeh Kazemi - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Mehdi Zarshenas - Department of Phytopharmaceuticals (Traditional medicine), School of Pharmacy, Shiraz University of Medical sciences, Shiraz, Iran.
Mohammad Miaad Shahrizi - Department of Phytopharmaceuticals (Traditional medicine), School of Pharmacy, Shiraz University of Medical sciences, Shiraz, Iran.
Maryam Sadat Sadati - Molecular Dermatology Research Center, Shiraz University of Medical Sciences.
Seyed Hossein Owji - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical sciences, Shiraz, Iran AND Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
خلاصه مقاله:
Reza Kaboodkhani - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohsen Sarikhani - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Tayebeh Kazemi - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Mehdi Zarshenas - Department of Phytopharmaceuticals (Traditional medicine), School of Pharmacy, Shiraz University of Medical sciences, Shiraz, Iran.
Mohammad Miaad Shahrizi - Department of Phytopharmaceuticals (Traditional medicine), School of Pharmacy, Shiraz University of Medical sciences, Shiraz, Iran.
Maryam Sadat Sadati - Molecular Dermatology Research Center, Shiraz University of Medical Sciences.
Seyed Hossein Owji - Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical sciences, Shiraz, Iran AND Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction:Many studies have been done on the use of aloe vera in wound healing, but fewer studies were done on the influence of this material on the reduction of the alar scar. Therefore, we evaluated the effect of a newly made aloe vera cream on alar wound healing after rhinoplasty.Materials and Methods:This was a randomized, double-arm, parallel-group, double-blind controlled trial and was done from June ۲۰۲۱ to February ۲۰۲۲. External wedge resection was done for all patients. The patients were randomly assigned to receive aloe vera cream (n=۳۱) (intervention group) or Face Doux cream (comparison group) (n = ۲۹). A pharmacist prepared the aloe vera cream. The primary outcome measure was the wound scar status which was assessed by two Questionnaires, including the mean Patient Scar Assessment Questionnaire (PSAQ) and Vancouver Scar Scale (VSS). Randomization and Blinding were done.Results:The mean PSAQ was significantly lower in group A after two weeks (۲۶.۹ versus ۳۱.۵, P<۰.۰۰۱), after two months (۱۵.۷ versus ۱۹.۶, P=۰.۰۴), and six months follow-up (۸.۸ versus ۱۱.۸, P=۰.۰۰۵). The mean VSS was significantly lower in group A after two weeks (۵.۶ versus ۷.۱, P=۰.۰۰۱), after two months (۳.۵ versus ۴.۹, P=۰.۰۰۲), and six months (۱.۲ versus ۲.۷, P<۰.۰۰۱). Repeated measurement analysis showed that both interventions significantly affected PSAQ and VSS.Conclusion:Although both interventions had a significant effect on PSAQ and VSS, compared to Face Duox, the topical use of Aloe Vera cream significantly reduced scar formation after alar resection, both statistically and clinically.
کلمات کلیدی: Aloe vera, cicatrix, Wound healing, Rhinoplasty
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1973366/