Encapsulation of probiotics by Electrospinning: Advances, Challenges and future prospects

Publish Year: 1402
نوع سند: مقاله کنفرانسی
زبان: English
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SENACONF12_129

تاریخ نمایه سازی: 16 خرداد 1403

Abstract:

Electrospinning, a cutting-edge nanofabrication technique, holds the potential to significantly enhance the survival and efficacy of probiotics, offering innovative solutions to address challenges associated with their delivery and viability. This review abstract explores the application of electrospinning in improving probiotic viability by encapsulating them within protective nanofiber matrices. The technique allows precise control over fiber morphology, diameter, and composition, tailoring encapsulation systems to safeguard probiotics from harsh gastrointestinal conditions. Electrospun nanofibers provide a protective barrier that shields probiotics from gastric acids and digestive enzymes, enabling their controlled release within the targeted gastrointestinal segments. This controlled release not only enhances probiotic survival but also facilitates sustained colonization and interactions with the host microbiota. Challenges such as optimal polymer selection, uniform probiotic distribution, and long-term stability are discussed, along with emerging applications and future prospects. Electrospinning's potential to revolutionize probiotic delivery and efficacy marks a pivotal advancement at the intersection of nanotechnology and microbiology, promising to unlock new avenues for personalized and effective health interventions.

Authors

Negin Shokrollahzadeh

Department of Microbial Biotechnology, Faculty of Basic Sciences and Modern Biological Technologies, University of Science and Culture, Tehran

Seyed Amirali Anvar

Department of food Hygiene, Science and Research Branch, Islamic Azad University, Tehran, Iran

Mojtaba Mohammadzadeh Vazifeh

Department of Microbial Biotechnology, Faculty of Basic Sciences and Modern Biological Technologies, University of Science and Culture, Tehran