Ammar Radhi Obaid - Department of Chemistry, Faculty of Basic Sciences, Ilam University, P. O. Box ۶۹۳۱۵۵۱۶, Ilam, Iran
Lotfi Shiri - Department of Chemistry, Faculty of Basic Sciences, Ilam University, P. O. Box ۶۹۳۱۵۵۱۶, Ilam, Iran

In this work, an efficient procedure for the synthesis of pyrazole derivatives via a one-pot multi-component reaction of phenyl hydrazine, malanonitrile, and various aromatic aldehydes using CoFe۲O۴@SiO۲@CPTES@Melamine as a magnetic nanocatalyst in water under room temperature conditions is reported. This nanocatalyst was synthesized in several steps and identified by various techniques including Fourier-transform infrared (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM) techniques. The advantages of using this magnetic nanocatalyst in this research include easy synthesis, efficiency, non-toxicity, high-efficiency product production, short reaction time, and reusability.

۵-Amino-۱H-pyrazole-۴-carbonitrile, Phenylhydrazine, Malononitrile benzaldehyde