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Herbicidal and Insecticidal Activity of Secondary Metabolites from Endophytic and Soil Fungi

عنوان مقاله: Herbicidal and Insecticidal Activity of Secondary Metabolites from Endophytic and Soil Fungi
شناسه ملی مقاله: JR_JASTMO-26-4_012
منتشر شده در در سال 1403
مشخصات نویسندگان مقاله:

S. Abdelgaleil - Department of Pesticide Chemistry and Technology, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria ۲۱۵۴۵, Egypt.
Y. Shiono - Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, ۹۹۷-۸۵۵۵, Japan.
N. E. M. Taktak - Department of Tropical Health, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
M. M. G. Saad - Department of Pesticide Chemistry and Technology, Faculty of Agriculture, El-Shatby, Alexandria University, Alexandria ۲۱۵۴۵, Egypt.

خلاصه مقاله:
Fungi are a good source for lead molecules in drug discovery and development. However, many compounds derived from fungi were not evaluated for their bioactivity against economic, agricultural, and public health pests. Twelve fungal secondary metabolites (۱-۱۲) were evaluated for herbicidal activity against Silybum marianum and insecticidal activity against Culex pipiens larvae. Among the tested metabolites, brefeldin A (۶) and ۶-eopxy-۴-hydroxy-۳-methoxy-۵-methyl-cyclohex-۲-en-۱-one (۱۱) showed potent herbicidal activity against S. marianum with complete inhibition of seed germination at ۵۰۰ mg L−۱. Compound ۶ revealed an exceptional herbicidal activity as it caused complete inhibition of root growth and strong reduction in shoot growth (I = ۷۴.۵%) and germination (۱۰.۰%) at ۲۵ mg L−۱. In addition, dehydroaustin (۹), phomaxanthone A (۴) and deacetylphomaxanthone A (۵) displayed a potent toxicity against fourth larval instar of C. pipiens with LC۵۰ values of ۳.۲۷, ۵۷.۰۳ and ۶۳.۵۰ mg L−۱, respectively. Based on the results of this study, compounds ۴-۶, ۹ and ۱۱ should be developed as natural pesticides.

کلمات کلیدی:
Bioactivity, Culex pipiens, Fungal metabolites, Natural products, Silybum marianum

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/2023181/