Nikolaos Trakas - Department of Biochemistry, Sismanogleio Hospital, Athens, Greece
Vasiliki Epameinondas Georgakopoulou - Pulmonology Department, Laiko General Hospital, Athens, Greece
Despoina Melemeni - Pulmonology Department, Sismanogleio Hospital, Athens, Greece
Christos Damaskos - ۱. Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece ۲. N.S. Christeas Laboratory of Experimental
Konstantinos Mantzouranis - Pulmonology Department, Sismanogleio Hospital, Athens, Greece
Nikolaos Garmpis - ۱. Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece ۲. N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National
Aikaterini Gkoufa - First Department of Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Petros Papalexis - First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Serafeim Chlapoutakis - Department of Thoracic Surgery, Agios Savvas Hospital, Athens, Greece
Pagona Sklapani - Department of Cytology, Mitera Hospital, Athens, Greece
Dimitrios Mermigkis - Pulmonology Department, Sismanogleio Hospital, Athens, Greece
Agathi Lekkakou - Pulmonology Department, Sismanogleio Hospital, Athens, Greece
Xanthi Tsiafaki - Pulmonology Department, Sismanogleio Hospital, Athens, Greece

Background: Cigarette smoking is the most important preventable cause of several diseases such as malignancies, pulmonary and cardiovascular diseases. Smoking cessation is now supported by both behavioral counseling and medical pharmacotherapy and is the only effective approach for slowing down an accelerated decline in forced expiratory volume in one second (FEV۱). Our study aims to examine changes in forced expiratory volume in one second (FEV۱) after smoking cessation for smokers attending our smoking cessation clinic their correlation to smokers’ demographic characteristics.Methods: ۱۱۴ smokers (۴۸ males and ۶۶ females), with a mean age of ۴۸.۳۶±۱۰.۴۹ years, were enrolled. They were classified in ۴ groups, according to their age; <۴۰ years (Group Α), ۴۱-۵۰ years (Group Β), ۵۱-۶۰ years (Group C), >۶۰ years (Group D) and underwent Spirometry on the ۱st day of visit, one month (۲nd visit) and, ۳ months later (۳rd visit).Findings: Statistically significant increase in FEV۱ values at the ۲nd and ۳rd visit compared to the ۱st visit was observed in smokers who quit smoking in Group Α, B and C (p<۰.۰۵). In addition, a statistically significant decrease in FEV۱ values at the ۲nd and ۳rd visit compared to the ۱st visit was noticed in smokers who continued smoking in Group B, C and D (p<۰.۰۵).Conclusion: Smoking cessation achieved through smoking cessation support led to the improvement of FEV۱ values within ۳ months. The greatest benefit was observed in smokers under the age of ۶۰.

Forced Expiratory Volume, smoking cessation, Tobacco Smoking, Spirometry