Woranan Witthayapipopsakul - Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK
Shaheda Viriyathorn - International Health Policy Program, Ministry of Public Health, Nonthaburi, Thailand
Salisa Rittimanomai - International Health Policy Program, Ministry of Public Health, Nonthaburi, Thailand
Jan van der Meulen - Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK
Viroj Tangcharoensathien - International Health Policy Program, Ministry of Public Health, Nonthaburi, Thailand
Ipek Gurol-Urganci - Department of Health Services Research and Policy, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK
Anne Mills - London School of Hygiene & Tropical Medicine, London, UK

Background  Various features in health insurance schemes may lead to variation in healthcare. Unwarranted variations raise concerns about suboptimal quality of care, differing treatments for similar needs, or unnecessary financial burdens on patients and health systems. This realist review aims to explore insurance features that may contribute to healthcare variation in Asian countries; and to understand influencing mechanisms and contexts. Methods  We undertook a realist review. First, we developed an initial theory. Second, we conducted a systematic review of peer-reviewed literature in Scopus, MEDLINE, EMBASE, and Web of Science to produce a middle range theory for Asian countries. The Mixed Methods Appraisal Tool (MMAT) was used to appraise the methodological quality of included studies. Finally, we tested the theory in Thailand by interviewing nine experts, and further refined the theory. Results  Our systematic search identified ۱۴ empirical studies. We produced a middle range theory in a contextmechanism-outcome configuration (CMOc) which presented seven insurance features: benefit package, cost-sharing policies, beneficiaries, contracted providers, provider payment methods, budget size, and administration and management, that influenced variation through ۲۰ interlinked demand- and supply-side mechanisms. The refined theory for Thailand added eight mechanisms and discarded six mechanisms irrelevant to the local context.  Conclusion  Our middle range and refined theories provide information about health insurance features associated with healthcare variation. We encourage policy-makers and researchers to test the CMOc in their specific contexts. Appropriately validated, it can help design interventions in health insurance schemes to prevent or mitigate the detrimental effects of unwarranted healthcare variation.

Health Insurance, Healthcare Variation, Medical Practice, Asia, Thailand