Oral leukoplakia: Diagnosis and treatment

Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JOHOE-5-2_002

تاریخ نمایه سازی: 17 مرداد 1403

Abstract:

BACKGROUND AND AIM: Oral leukoplakia (OL) is a common premalignant lesion. The possible benefits of specific interventions in preventing a malignant transformation of OL are not well understood. This review assesses different invasive treatment techniques for OL and evaluate the optimal treatment possibilities.METHODS: A Medline (PubMed) search was conducted and heterogeneity between the studies was found, e.g., with regard to the OL lesions, patient groups, follow-up time, and definition of recurrence.RESULTS: The recurrence and malignant transformation rate after the different treatment methods were evaluated. The mean overall recurrence rate varied with the treatment method.CONCLUSION: A surgical treatment appears to decrease the risk of transformation but does not fully eliminate it. Follow-up should be done regardless of the surgical treatment.

Authors

Marie Kjaergaard Larsen

Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark

Jens Ahm Sørensen

Professor, Department of Plastic and Reconstructive Surgery, Odense University Hospital, Odense, Denmark

Christian Godballe

Professor, Department of ORL-Head and Neck Surgery, Odense University Hospital, Odense, Denmark

Torben Henrik Thygesen

Associate Professor, Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark

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