Seyed Mansoor Rayegani
Mohammad Hasan Bahrami
Darisuh Eliaspour
Seyed Ahmad Raeissadat
Mostafa Shafi Tabar Samakoosh
Leyla Sedihgipour
Elham Kargozar

Abstract Introduction: Carpal Tunnel Syndrome (CTS) is the most common type of entrapment neuropathy. Conservative therapy is usually considered as the first step in the management of CTS. Low Level Laser Therapy (LLLT) is among the new physical modalities, which has shown therapeutic effects in CTS. The aim of the present study was to compare the effects of applying LASER and splinting together with splinting alone in patients with CTS.Methods: Fifty patients with mild and moderate CTS who met inclusion criteria were included in this study. The disease was confirmed by electrodiagnostic study (EDx) and clinical findings. Patients were randomly divided into ۳ groups. Group A received LLLT and splinting. Group B received sham LLLT+ splinting and group C received only splints. Group A received LLLT (۵۰ mw and ۸۸۰nm with total dose of ۶ joule/cm۲). Clinical and EDx parameters were evaluated before and after treatment (۳ weeks and ۲ months later).Results: Electrophysiologic parameters and clinical findings including CTS provocative tests, Symptoms severity score (SSS), Functional Severity Score (FSS) and Visual Analogue Score (VAS) were improved in all three groups at ۳ weeks and ۲ months after treatment. No significant changes were noticed between the three groups regarding clinical and EDX parameters.Conclusion: We found no superiority in applying Low Intensity Laser accompanying splinting to traditional treatment which means splinting alone in patients with CTS. However, future studies investigating LLLT with parameters other than the one used in this study may reveal different results in favor of LLLT. Keywords: Low level Laser Therapy CTS electrodiagnosis