Leila Zareian Baghdadabad - Department of Biology, Medical Biotechnology Research Center, Yazd University, Yazd, Iran
Sheyda Shahivand - Department of Biology, Medical Biotechnology Research Center, Yazd University, Yazd, Iran
Parastoo Pourmandi - Department of Biology, Medical Biotechnology Research Center, Yazd University, Yazd, Iran
Mina Rezayat - School of Medicine, Zanjan University of Medical Sciences, Tehran, Iran
Fateme Guitynavard - Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Fardin Asgari - School of Medicine, Zanjan University of Medical Sciences, Tehran, Iran
Vahid Abedi yarandi - Tehran university of Medical Sciences

Introduction: According to the effect of hypertension on kidney stone formation and on the other hand, there is no research to evaluate the impact of hypertension on the location of stone formation in kidney, so the aim of present study was assessing the effect of hypertension on the location of stone formation in kidney.Methods: Data for present investigation were prepared by Persian Registry for Stones of Urinary System (PERSUS). This investigation was retrospective cohort and the study initially enrolled ۵۱۳۰ participants from ۲۰۲۰ to ۲۰۲۴. Participants with history of hypertension were selected and categorized as exposure group (n= ۳۹۶). Participants without medical history and norm-tension were categorized as non-exposure group (n=۳۹۶). Diagnosis of kidney stone was approved by CT-scan and data of medical history were collected by interview with patients.Results: The mean age of participants was ۴۸.۸۳±۱۳.۶۲ years. The distribution of kidney stone location was not significantly difference between two groups (P-value=۰.۱). The number of kidney stones in left and right kidney were not difference between patients with hypertension history and patients with norm-tension history (P-value=۰.۷۲, P-value=۰.۲۵).  There were no significant differences in stone formation in various parts of kidney between participants with hypertension and norm-tension history (P-value=۰.۱۶). Conclusion: Hypertension increased the risk of kidney stone formation but did not affect the location of stone formation in kidney.

Hypertension, Stone Formation, Kidney