The role of olfactory bulb in epilepsy: emphasizing on its connection with hippocampus

Epilepsy is a neurological disorder characterized by recurrent seizures resulting from abnormal neuronal activity in the brain. The olfactory system is implicated in temporal lobe epilepsy (TLE), and some areas of the olfactory system may serve as sources of seizures. TLE patients often experience olfactory sensations or auras before seizure onset, and olfactory stimulation has been shown to modulate or suppress seizure activity. The connection between the OB and certain brain areas, including the hippocampus, plays a significant role in the spread and propagation of seizure attacks. The document highlights the anatomical and functional relationship between the OB, entorhinal cortex, and hippocampus, suggesting that the olfactory system is involved in the pathogenesis of epilepsy.

Keywords:

Epilepsy , Seizure , Olfactory bulb , Hippocampus