Mehdi Si rouspour - Department of Chemi stry, Science and Research Branch, Islamic Azad Uni versity, Boroujerd, Iran
Sanaz souri - Department of Chemi stry, Science and Research Branch, Islamic Azad Uni versity, Boroujerd, Iran
Azade Havasian - Department of Chemi stry, Science and Research Branch, Islamic Azad Uni versity, Boroujerd, Iran

This study includes designing and optimization of a synthetic method to prepare the ethyl [ 2-(4-methoxy phenyl)-1-methyl ethyl]-Amin compound as the raw material in the synthesis of mebeverine. This compound is formed in a direct Reductive aminatione reaction from the reaction of 4-methoxy phenyl acetone and ethyl Amin under the condition of Isopropanol solvent and Sodium cyanotrihydridobora Catalyst in the room temperature .

ethyl -[2-(4-methoxy-phenyl)-1-methyl-ethyl]–amin, 4-methoxy phenyl acetone, Reductive amination, Sodium cyanoborohydride (NaBH3CN)