A facile chemical method to produce -Fe2O3@SiO2-PW nanoparticles as a novel magnetically-recoverable catalyst for fischer indole synthesis

A new type of magnetically-recoverable catalyst was synthesized by the immobilization of H3PW12O40 on the surface of silica-encapsulated -Fe2O3 nanoparticles. We demonstrate that the - Fe2O3@SiO2-PW can act as an efficient catalyst for the Fischer Indole Synthesis under mild conditions, withthe reaction reaching completion in short reaction time. The influence of the preparation conditions on the catalytic activities of the hybrids is also investigated. The yields of Various indole derivatives were 70–95%. The The heterogeneous -Fe2O3@SiO2-PW could be easily recovered and reused for at least six times without significant loss in activity

Keywords:

Fischer indole synthesis , magnetically-recoverable catalyst , heterogeneous , indole