Efficient and Green One-Pot Synthesis of Pyrano pyrazole Derivatives by Recyclable Nano-manganese Catalyst in Water Media
عنوان مقاله: Efficient and Green One-Pot Synthesis of Pyrano pyrazole Derivatives by Recyclable Nano-manganese Catalyst in Water Media
شناسه ملی مقاله: TCPCO01_113
منتشر شده در اولین همایش ملی تکنولوژی های نوین در شیمی و پتروشیمی در سال 1393
شناسه ملی مقاله: TCPCO01_113
منتشر شده در اولین همایش ملی تکنولوژی های نوین در شیمی و پتروشیمی در سال 1393
مشخصات نویسندگان مقاله:
Arezoo Moharami - Department of Chemistry, School of Science, Azzahra University, Vanak,Tehran ۱۲۳۴, Iran
Majid. M Heravi - Department of Chemistry, School of Science, Azzahra University, Vanak,Tehran ۱۲۳۴, Iran
خلاصه مقاله:
Arezoo Moharami - Department of Chemistry, School of Science, Azzahra University, Vanak,Tehran ۱۲۳۴, Iran
Majid. M Heravi - Department of Chemistry, School of Science, Azzahra University, Vanak,Tehran ۱۲۳۴, Iran
A clean, simple, one-pot, synthesis of some important pyranopyrazole derivatives via a four-component tandem reaction of aromatic aldehydes, ethylacetoacetate, malononitril and hydrazine hydridein the presence of nano- Mn(bpdo)2Cl2/MCM-41 as catalyst was carried out under green and environmentallybenign conditions because of water media leads to 6-amino-3-alkyl-4-aryl-5-cyano-1,4-dihydro pyrano [2,3-c] pyrazol. They have useful biological and pharmacological properties, such as antimicrobial, insecticidal,anticancer, and anti-inflammatory. Furthermore, some of these compounds are commonly in employment suchas cosmetics and pigments. The aqueous medium and the reaction with green and recyclable nanocatalysis offer a fast and eco-friendly method for the synthesis of pyranopyrazoles. This method has advantages including mild condition, short reaction time, and high yield, using nanocatalysis as a nontoxic and recyclable catalysis and using water as a clean solvent.
کلمات کلیدی: Pyrano pyrazole derivatives, Tandem reaction, Nano-manganese Catalyst, Green reaction
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/244338/