Prepration of synthetic rotein nanoparticles as drug delivery vehicles
عنوان مقاله: Prepration of synthetic rotein nanoparticles as drug delivery vehicles
شناسه ملی مقاله: NICEC09_090
منتشر شده در نهمین کنگره ملی مهندسی شیمی ایران در سال 1383
شناسه ملی مقاله: NICEC09_090
منتشر شده در نهمین کنگره ملی مهندسی شیمی ایران در سال 1383
مشخصات نویسندگان مقاله:
Aghajani - Biotechnology group, Dept.of Chemiacl Engineering, School of engineering, Tarbiat Modarres University
Jahashahi - Nanoparticleslab, Dept.of Chemical Engineering, Faculty of engineering, University of Mazandaran (UMZ)
S.A. Shojaosadati - Biotechnology group, Dept.of Chemiacl Engineering, School of engineering, Tarbiat Modarres University
خلاصه مقاله:
Aghajani - Biotechnology group, Dept.of Chemiacl Engineering, School of engineering, Tarbiat Modarres University
Jahashahi - Nanoparticleslab, Dept.of Chemical Engineering, Faculty of engineering, University of Mazandaran (UMZ)
S.A. Shojaosadati - Biotechnology group, Dept.of Chemiacl Engineering, School of engineering, Tarbiat Modarres University
Pharmaceuical industry can widly use protein nanostructure because they mimic the drug delivery vehicles such as viruses,at the same time they are non-antigenic and biodegradable. This study objects to manufacture bovine serum albumin (BSA) nanoparticle by coacervation method following by crosslinking with glutaraldehyde. It is shown that the shape of nanoparticles is semispherical and the size distribution of them is 80- 280 nm. The mean size is 150 nm.The particl size is critical parameter in particular for invivo behaviour of nanoparticles after injection.
کلمات کلیدی: Bovine serum albumin, nanoparticles, coaccervation method, drug delivery system
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/29470/