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Paper
Title

Molecular-Friendly Histopathology

Year: 1384
COI: JR_IJP-1-1_001
Language: EnglishView: 572
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Authors

Mehdi Nassiri - University of Miami, Jackson Memorial Hospital, Miami, Florida
Mehrdad Nadji - University of Miami, Jackson Memorial Hospital, Miami, Florida

Abstract:

The rapidly expanding fields of pharmacogenomics and pharmacodiagnostics havepresented the pathology laboratories with many challenges and opportunities. As custodiansof patient tissues, these laboratories are in the logical position to perform biomoleculartesting for proper management of patients. In order to meet these challenges, the pathologylaboratories of the twenty-first century should design and execute a biomarker-friendly,standardized tissue handling, including fixation and processing, to ensure uniform protectionof macromolecules for clinically useful molecular assays. This important pre-analytic phasecannot be successful if tissues are handled in the traditional manner that includes the useof conventional fixation and processing. The recent progress in fixation and processingmethods are rapidly replacing the time-honored routine formalin fixation and overnightprocessing. In this article we describe our experience with such system that not only producesgood histomorphology but also preserves high quality RNA, DNA, and proteins in paraffinembedded material.

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Paper COI Code

This Paper COI Code is JR_IJP-1-1_001. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/302520/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Nassiri, Mehdi and Nadji, Mehrdad,1384,Molecular-Friendly Histopathology,https://civilica.com/doc/302520

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COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

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