A Comparative Study on Instrumental Precision of Refrigerated and Non-Refrigerated Auto-Analyzers in Order to Improve Quality Assurance in Biochemistry Laboratory
Publish place: IRANIAN JOURNAL of PATHOLOGY، Vol: 2، Issue: 3
Publish Year: 1386
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJP-2-3_002
تاریخ نمایه سازی: 5 آبان 1393
Abstract:
Background and Objective: Quality control is one of the most important components in order to improve quality assurance in laboratories during analytical steps. For this purpose, coefficientof variation plays an important role. Due to the fast improvement in technology, application of inferential statistics for the comparisons of laboratory techniques, including instrument and chemicals and fast replacement of them would be technically essential.Materials and Methods: In this research study, we tried to determine the precision of one auto-analyzer with refrigerator and the other one without such facility for the analysis of glucose,triglyceride and cholesterol in 30 successive days and compared the coefficient of variations that arean important factor for analytical precision. Results: Comparing the means of aimed groups by paired t-test with P=0.05 in measurement ofglucose, triglyceride and cholesterol showed that there was no significant difference between the two instruments. In determination of glucose, triglyceride and cholesterol by auto-analyzer with refrigerator, CV% of these analytes was 1.3%, 1.4%, and 0.9% respectively. By the auto-analyzerwithout refrigerator, the CV% of those analytes was 1.5%, 2.5% and 1.11% respectively. Conclusion: There is reasonably higher precision for auto-analyzer with refrigerator than the other one.
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Authors
Hossein Ayatollahi
Dept. of Biochemistry and Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
Tayyebeh Kianoush
Dept. of Biochemistry and Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
Nema Mohammadian Roshan
Dept. of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran