Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها

The Diagnostic Value of Serum IgG-Antigliadin, IgA Anti-endomysial and IgA Anti-tissue Transglutaminase Antibodies for Pediatric Celiac Disease

Year: 1387
COI: JR_IJP-3-4_008
Language: EnglishView: 513
This Paper With 5 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 5 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:


Mitra Mehrazma - Dept. of Pathology, Iran University of Medical Sciences, Tehran, Iran.
Alireza Abdollahi - Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran.
Elham Talachian - Dept. of Pediatrics, Iran University of Medical Sciences, Tehran, Iran.


Background and Objective: Celiac disease is an autoimmune disorder, characterized by inflammation, villous atrophy, and crypt hyperplasia of the small bowel mucosa. In this studywe considered and compared sensitivity and specificity of serological tests in patients with celiac disease.Materials and Methods: In this cross-sectional study we prospectively recruited children with suspected celiac disease. An intestinal biopsy specimen was obtained from all patients. Celiac diseasediagnosed on the basis of histologic findings of Marsh classification. A serum sample was taken atthe time of biopsy for serologic tests. Findings were analyzed using SPSS program, t-test, and chisquare tests.Results: Out of a total of 134 children in this study, seventy (52.21%) patients were boy and sixty four (47.8%) patients were girl. Celiac disease was diagnosed in 14 (10.4%) of the patients.In serologic tests, 11 patients (78.6%) were positive for antigliadin-Ab, 4 (28.6%) for anti tissuetransglutaminase Ab, and 9 (64.3%) for antiendomysial antibody. Sensitivity of antigliadin-Ab was 78.6% and its specificity was 95.9%. Sensitivity of anti tissue-transglutaminase Ab was 28% and itsspecificity was 95%. Sensitivity of antiendomysial Ab was 64% and its specificity was 96%. Conclusion: Positive serologic tests are supportive of the diagnosis in those with characteristic histopathologic changes on small intestinal biopsy. The best tests for this purpose are the IgAantiendomysial antibody or IgA anti tissue-transglutaminase, both of which are highly sensitive and specific.


Paper COI Code

This Paper COI Code is JR_IJP-3-4_008. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Mehrazma, Mitra and Abdollahi, Alireza and Talachian, Elham,1387,The Diagnostic Value of Serum IgG-Antigliadin, IgA Anti-endomysial and IgA Anti-tissue Transglutaminase Antibodies for Pediatric Celiac Disease,

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.


The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 4,659
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

New Papers

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.