Coexistant of Fabry Disease and IgA Glomerulonephritis in a 39 Year Old Male

Anderson-Fabry disease is a rare inherited X-linked lysosomal storage disease caused by deficiency of the enzyme alpha-galactosidase A. Hereby we report a 39 year old male that presented withproteinuria and edema. Histopathologic, immunofluorescence and ultrastractural examination ofrenal tissue were in favor of Fabry disease in associate with IgA nephropathy. Fabry’s disease associated with IgA nephropathy apparently is extremely rare, and the present case is among few reported cases in literature

Keywords:

Fabry disease , IgA Glomerulonephritis , Iran