Eight-year Study of Mycobacterium tuberculosis in Mashhad, Northeast of Iran

Background & Objectives: Tuberculosis is one of the greatest health problems in Iran. The distribution of the disease is not equal in all parts of the country. The aim of this study was to evaluate the frequency of positive results for Mycobacterium tuberculosis in samples referred to an academic hospital in an 8 year period. Materials and Methods: The samples from different wards of Qaem Hospital, Mashhad and samples referred to Outpatient Clinic during the years 2001-2008 and 75 samples from the prison in the same period were analyzed with direct microscopy of smear and culture methods for M.tuberculosis. Basic descriptive statistics were performed using SPSS 11.5 software. Results: A total 26817 samples were analyzed and the results showed that the frequency ofMycobacterium positive samples in hospitalized patients’ samples was 2412 (9%) with microscopyand 1573 (6%) with culture method. In the outpatients, it was 897 (10.2%) and 417 (4.7%) withmicroscopy and culture methods, respectively. Form 75 samples from the prison, 9 (12%) were positive with microscopy method. Culture method yielded only one (1.3%) positive result in these samples. Conclusion: The frequency of M. tuberculosis was relatively high in the study groups. Therefore it seems continues surveillance is essential to monitor the M. tuberculosis in hospitals and community.

Keywords:

Mycobacterium tuberculosis , Epidemiology , Iran