Antiparasitic efficacy of worm wood (Artemisia absinthium)alcoholic extract on syphacia obvolata
Publish place: Iranian Journal of Veterinary Medicine، Vol: 6، Issue: 1
Publish Year: 1391
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJVM-6-1_009
تاریخ نمایه سازی: 26 اردیبهشت 1394
Abstract:
ACKGROUNDS: Occurrence of resistance against antiparasitic drugs has made it essential for researchers to find new sources for antiparasitic drugs. OBJECTIVES: This study was performed to determine the efficiency of alcoholic extract of worm wood (Artemisia absinthium) on Syphasia parasite. METHODS: Artemisia absinthium extract was examined on 3 groups of mice at 2.5%, 5% and 10% concentrations. A group of positive controlreceived pyrantel pamoate, while negative control group was treated by a solution containing no extract. Mice were treated orally 28 days after infection by Syphacia eggs. The efficacy of treatment was determined by Syphacia eggs in the feces. RESULTS: In groups that received either 5% or 10% concentrations of A. absinthium extract or pyrantel pamoate, microscopic examinations of the feces demonstrated no Syphacia eggs. CONCLUSIONS: Data obtainedfrom the present study showed that the alcoholic extract of Artemisia absinthium may lead to a decline in the number of Syphacia eggs in the feces with minimal side effects. The extract of this plant can probably be used as a suitable alternative in the treatment of some parasitic diseases.
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Authors
M.R Youssefi
Department of Veterinary Parasitology, Babol-Branch, Islamic Azad University,Babol, Iran.
M Abuhosseini Tabari
Department of Veterinary Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
G Sadeghi Hashjin
Department of Veterinary Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
M.K Kouhi
Department of Veterinary Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.