Aphylogenetic study on the NP gene of detected caninedistemper virus in (2008-2011) Iran
Publish place: Iranian Journal of Veterinary Medicine، Vol: 8، Issue: 3
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJVM-8-3_002
تاریخ نمایه سازی: 26 اردیبهشت 1394
Abstract:
BACKGROUND: Canine Distemper (CD) is a lethal systemic disease affecting a wide variety of terrestrial carnivores. OBJECTIVES: This study was performed to survey epidemiological and molecular characteristics of the canine distemper virus (CDV) strains circulating in Iran. METHODS: In this stud y, 19 CDV-suspected unvaccinated dogs from Northeast and center of Iran were analyzed for presence of CDV nucleoprotein (NP) gene using Nested-PCR during 2008- 2011. Different biological samplesof 14 dogs were positive. RESULTS: The phylogenetic analysis based on partial NP gene sequences indicated the presence of two major clusters that are clearly different from vaccine strains in Iran. One cluster belongs to the European group and the other one to the Arctic group. CONCLUTIONS: Due to a lack of phylogeneticanalysis on CDV in countries bordering Iran, except Turkey, the ancestor of Iranian sequences specially Iranian Arctic sequences could not be definitely identified. This study is the first report on phylogenetic analysis of CDV from domestic dogs in Iran.
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Authors
S Namroodi
Department of Environmental Sciences, Faculty of Fisheries and Environmental Sciences, Gorgan University ofAgricultural Sciences & Natural Resources, Gorgan, Iran
A Rostami
Department of Internal Medicin, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
K Majidzadeh Ardebili
Faculty of Medicine, Army University of Medical Sciences, Tehran, Iran
A Ghalyanchi Langroudi
Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran