Omid Louie - Department of Chemistry, Payame Noor University, P.O. BOX ۱۹۳۹۵-۴۶۹۷,Tehran, Iran
Abdoulhossien Massoudi - Department of Chemistry, Payame Noor University, P.O. BOX ۱۹۳۹۵-۴۶۹۷,Tehran, Iran
Soodabe Ramezani - Department of Chemistry, Payame Noor University, P.O. BOX ۱۹۳۹۵-۴۶۹۷,Tehran, Iran

The amphiphilic graft copolymer using chitosan (CS) as hydrophilic segment and poly (L-lactic acid) (PLLA) as hydrophobic segment, was prepared through a protection-graft-deprotection route. A simple and convenient procedure for chemo selectively protecting the amino groups of CS was developed to provide N-phthaloyl-chitosan (PHCS) that is indispensable as a soluble N-protected precursor forfurther controlled modification reaction of CS. The weight percent PHCS-g-PLLA copolymer was determined by the theoretical models based on experimental data. Low error regression in new modelswas monitored.

Chitosan, PHCS-g-PLLA, CS-g-PLLA, graft copolymer