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Title

Investigating the Mechanical Properties of Polycaprolactone/triclosan loaded poly(lactic-acid) nanoparticles composites

Year: 1393
COI: ICHEC15_614
Language: EnglishView: 926
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Authors

Saeed Davoodi - School of Chemical Engineering, College of Engineering, University of Tehran,P.O. Box ۱۱۳۶۵-۴۵۶۳, Tehran, Iran
Babak Kaffashi - School of Chemical Engineering, College of Engineering, University of Tehran,P.O. Box ۱۱۳۶۵-۴۵۶۳, Tehran, Iran
Seyed Mohammad Davachi - School of Chemical Engineering, College of Engineering, University of Tehran,P.O. Box ۱۱۳۶۵-۴۵۶۳, Tehran, Iran

Abstract:

The emergence of tissue engineering has increased the demand for a various set of biomaterials to support the development of tissues in vitro prior to implantation in vivo. Due to slow degradation of PCL, it is ideally suitable for long-term delivery extending over a period of more than one year. The aim of this work is to prepare nanocomposites based on PCL and PLLA/Triclosan nanoparticles with the antibacterial ability and enhanced mechanical properties for soft tissue engineering uses. Different content of nanoparticles (1-10%) were added to the PCL matrix inorder to give antibacterial property to matrix. Adding PLLA in the nano scale into PCL matrix improves the mechanical propeties of nanocomposites without decreasing the PCL toughness.Also, due to high crystallinity of PCL, it is expected to form a nanocomposite with more controled drug release and slower degradation rate compared with the PLLA scaffolds. The obtained composites will be an appropriate candidate for soft tissue engineering.

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This Paper COI Code is ICHEC15_614. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/368495/

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Davoodi, Saeed and Kaffashi, Babak and Davachi, Seyed Mohammad,1393,Investigating the Mechanical Properties of Polycaprolactone/triclosan loaded poly(lactic-acid) nanoparticles composites,15th Iranian Natioanl Congress of Chimical Engineering,Tehran,https://civilica.com/doc/368495

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  • Garkhal, Kalpna., Verma, Shalini., Jonnalagadda, S., Kumar, Neeraj., "Fast Degradable ...
  • Dash, Tapan K., Konkimalla, V. B., 2 2 Poly-e-c aprolactone ...
  • Delabarde, Claire., Plummer, Christopher J. G., Bourban, Pierre-Etienne. Manson, Jan-Anders ...
  • Chavalitpanya, Kamolrat., Phattanarudee, Siriwan., "Poly(lactic aci d)/Polyc aprolactone Blends C ...
  • Kugel, Alex J., Ebert, Scott M., Stafslien, Shane J., Hevus, ...
  • Davachi, Seyed Mohammad., Kaffashi, Babak., "Preparation and C haracterization of ...

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Type of center: دانشگاه دولتی
Paper count: 79,680
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