Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features
Publish place: IRANIAN JOURNAL of PATHOLOGY، Vol: 10، Issue: 1
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
View: 554
This Paper With 5 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
این Paper در بخشهای موضوعی زیر دسته بندی شده است:
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJP-10-1_012
تاریخ نمایه سازی: 13 مرداد 1394
Abstract:
Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessness for2 years. The CECT revealed multiple focal enhancing lesions along inferior mediastinal pleural surface and along lateral pleural surface. A thoracotomy and tumor excision was done and MPNST was diagnosed on microscopy and immunohistochemistry. This case highlights that this unusual tumor may involve lung parenchyma. So this possibility should be kept in mind in patients with intrathoracic mass.
Keywords:
Authors
Sunita Singh
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Megha Ralli,
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Sonia Hasija
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
Renuka Verma
Departmentof Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India