f.r Nikmaram - Department of Chemistry, Faculty of Science,Yadegar - e- Imam Khomeini (RAH)Branch, Islamic Azad University, Tehran
j Najafpourand - Department of Chemistry, Faculty of Science,Yadegar - e- Imam Khomeini (RAH)Branch, Islamic Azad University, Tehran
l Fattahian - Department of Chemistry, Faculty of Science,Yadegar - e- Imam Khomeini (RAH)Branch, Islamic Azad University, Tehran

In this study, the thermodynamic properties of the connection of Cis-Platin with Guanine have been investigated by B3LYP/ LANL2DZ level of density functional theory at thedifferent models of water solvent (PCM, IEFPCM, CPCM).The results show that the formation of cis-pt complex with guanine in CPCM model is more favorable than the other models.

Cis-Platin ; Guanine ;, Solvent Models ; DFT