Hamideh Basiri - Department of Life Science Engineering, University of Tehran, Tehran, Iran
Ali Abouei - Department of Life Science Engineering, University of Tehran, Tehran, Iran
Farhad Bakhshi - Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran
Sahba Mobini - Department of Embryology and Stem Cells, Reproductive Biotechnology Research Center, Avicenna Research

biomimetic carbonate-hydroxyapatite nanocrystals (CHA) have been designed and synthesized in order toobtain a remineralization of the altered enamel surfaces. Nano CHA shows strong affinity to the tooth, and canstrongly adsorb on enamel surfaces and induce changes in dental enamel crystallographic, mechanical properties andimprove dental remineralization by making new biomimetic apatitic mineral deposition which progressively fills thesurface scratches. The aim of this in vitro study was to evaluate the effect of Nano CHA on the remineralization ofhuman enamel, which was produced by wet chemical methods and characterized by XRD, FTIR remineralization. Inorder to evaluate the remineralization effect, the Vickers Hardness Number of the enamel surface was evaluated ateach step. Nano CHA with its good properties of biocompatibility, bioactivity and potential capacity for of dentalremineralization hasa wide range of applications in medical cases such as toothpastes and oral health compounds.

Hydroxyapatite; Remineralization; Synthesis; Nonstoichiometry