Sharareh Zirrahi - Department of Applied Chemistry, Faculty of Science, Shiraz Branch, Islamic Azad University,P.O. Box ۷۱۹۹۳-۵, Shiraz, Iran
Hamid Reza Safaei - Department of Applied Chemistry, Faculty of Science, Shiraz Branch, Islamic Azad University,P.O. Box ۷۱۹۹۳-۵, Shiraz, Iran;

A facile and direct synthesis of 1,3-thiazinane-2-thione derivatives via the one pot four-component coupling of carbon disulfide, benzyl amines, malonitrile and benzaldehyde derivetives under neutral conditions without solvent is reported. In this reaction tetra butyl ammonium bromide (TBAB) is used as a phase transfer catalyst

1,3-thiazinane-2-thione, carbon disulfide, TBAB, Multicomponent reaction