Synthesis of alkyl azides from alcohols by using cross-linked poly (4-vinyl pyridine) supported azide ion and by cyanuric chloride/dimethyl formamid

Since the preparation of the first organic azide, phenyl azide, by Peter Grieß in 1864 these energy-rich and flexible intermediates have enjoyed considerable interest. Industrial interest in organic azide compounds began with the use of azides for the synthesis of heterocycles such as triazoles and tetrazoles.[1]Recycled poly (4- vinyl pyridinium) azide is a reagent that provides mild reaction conditions. Cyanuric chloride is widely used reagent in organic functional groups transformation. Due to the disadvantages and limitations of existing methods for the preparation of alkyl azides and their importance in organic chemistry, in this study has tried to use solvent-free conditions and application of recyclable polymeric reagents as a source of azide, solving the above problems in this one–put reaction, alcohls efficiently were converted to alkyl azides by using cross-linked poly (4-vinyl pyridine) supported azide ion promoted by cyanuric chloride/dimethyl formamid. The reaction proceeded very well and produced desired product in good yield.

Keywords:

preparation of alkyl azides , solvent free , poly (4- vinyl pyridinium azide) , Cyanuric chloride