Zuraida Hanum - Student of Departement of Animal Science and Technology, Faculty of Animal Science, Bogor Agricultural University, Jl. Agatis, IPB Darmaga, Bogor 16680. Department of Animal Sciences, Faculty of Agricultural, Syiah Kuala University, Jl. Tgk. Hasan Krueng
Cece Sumantri - Departement of Animal Science and Technology, Faculty of Animal Science, Bogor Agricultural University, Jl.Agatis, IPB Darmaga, Bogor 16680.
Purwantiningsih - Department of Chemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Jl. Agatis, IPB Darmaga, Bogor 16680.
Irmanida Batubara - Department of Chemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Jl. Agatis,IPB Darmaga, Bogor 16680. Biopharmaca Research Center, Bogor Agricultural University, Bogor, Jl.Taman Kencana No. 3, Bogor, 16128

This study aimed to investigate the affectivity of goat milk fermented with Lactobacillus plantarum (TW 14) as melanin inhibitor. Prior to the treatment of melanin inhibitor, samples were pasteurized. After that, the samples were incubated at 37 oC for 24 hour and analyzed for lactic acid bacteriapopulation, total titratable acid, protein and fat contents. Fermented milk were extracted by centrifugation, the supernatant was collected and used forinhibition of tyrosinase enzymes activity and inhibitory melanin on B16F0 cell analysis. The results showed that the milk used complied with standardfermented milk which able to inhibit tyrosinase activity (L-DOPA Substrat). Goat milk was unable to inhibit melanin synthesis on B16F0 cell butfermented milk showed the ability, inhibit tyrosinase and melanin synthesis on B16F0 cell. A concentration fermented sample of 66.7 mg/ml resulted ina decrease in melanin concentration of extracellular in TW 14 treatment groups for 27%. In general goat milk fermented with lactic acid bacteria is an effective as melanin inhibitor.

Goat Milk, Fermentation, Lactobacillus Plantarum, Melanin Inhibitor