The association between iron status and some immunological factors in the pregnancy
Publish Year: 1390
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJRM-9-3_015
تاریخ نمایه سازی: 16 شهریور 1395
Abstract:
Iron deficiency anemia (IDA) is a common problem in many developing countries. It is still considered the most common nutrition deficiency worldwide. Apart from its direct hematologic importance, IDA affects cellular and humoral immunity and predisposes the host to infections (1).Pregnant women are highly prone to IDA. Controversial results are reported in studies targeting this group of patients. Tang et al showed a direct association between hemoglobin concentration and the count of CD4+ T-cell lymphocytes, serum levels of IL-2 and IgG, and an inverse association with susceptibility to infection (2). Ironically, Leush et al reported an increase in IgM and IgG in the second and third trimesters of pregnancy in women with IDA (3).With regard to controversial results and the scarcity of studies focusing on pregnant women, we aimed to enlighten the relation between iron status and some immunological factors include some component of complement system, IgA, IgM, IgG subclasses of immunoglobulins and pro-inflammatory cytokines during the third trimester of pregnancy.
Authors
Seyed Alireza Sobhani
Department of Pathology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Zahra Etaati
Department of Obstetrics and Gynecology, Hormozgan University of Medical Sciences, Bandar Abbas,Iran.
Sepideh Mirani
General physician, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Paknoosh Saberi
Department of Biochemistry, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.