Efficacy of the local endometrial injury in patients who had previous failed IVF-ICSI outcome
Publish Year: 1391
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJRM-10-6_010
تاریخ نمایه سازی: 16 شهریور 1395
Abstract:
Background: The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome. Objective: To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure. Materials and Methods: An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women. Results: Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03). Conclusion: Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome
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Authors
Mustafa Kara
Department of Obstetrics and Gynecology, Bozok University, Medical Faculty, Yozgat, Turkey
Turgut Aydin
Department of Obstetrics and Gynecology, Kayseri In vitro Fertilization Center, Kayseri, Turkey
Nurettin Turktekin
Department of Obstetrics and Gynecology, Kayseri In vitro Fertilization Center, Kayseri, Turkey
Karacavus s
Department of Nuclear Medicine, Bozok University Medical Faculty, Yozgat, Turkey.