The prevalence of icaADBC Genes among Clindamycin Inducible Resistant Staphylococcus aureus Isolates

Background: Clindamycin inducible resistant Staphylococcus aureus (S.aureus) isolates can cause failure in treatment with this antibiotic.Biofilm production via polysaccharide intercellular adhesion (PIA) contributes in the colonization of S. aureus, resulting in the initiation of different diseases. The aim of this study was to detect icaADBC genes among isolates of S.aureus with inducible resistance to clindamycin. Materials and Methods: A total of 209 clinical S.aureus isolates were collected and identified by conventional phenotypic tests. Isolates with inducible resistance to clindamycin were detected by double disk diffusion test (D-Test) using clindamycin (2

Keywords:

Staphylococcus aureus , inducible resistance , D-test , MRSA , icaADBC operon