Methods of microbial production of glucose oxidase (GOX)

Glucose oxidase production was optimized using an isolated strain of Aspergillus niger and penicillium amagasakiense. Effects of the polysaccharides alginate and locust bean gum, and oligosaccharides oligomannuronate (OM) and oligoguluronate (OG), on glucose oxidase (GOD) production by Penicillium variabile P16 were studied. The method of glucose oxidase production (β-D- glucose: oxidase 1- oxidoreductase, E.C.1.1.1.3.4.GOD) using the waste myceliums of Aspergillus niger is studied. The growth of many bacterial and fungal species is thus inhibited in the presence of GOD which, e.g., killed microsclerotia of Verticillium dahliae both in ¨itro and in sterile soil.

Keywords:

Glucose oxidase , Aspergillus niger , penicillium amagasakiense